Taking a pharmaceutical product candidate from discovery to market is a multi-step process that may take several years. The goal of employing Process Analytical Technology (PAT) during this period is to understand and control the manufacturing process, which is consistent with the FDA’s current drug quality system: quality cannot be tested into products; it should be built-in or should be by design. Increases in information provided by PAT during the development period may offer several advantages including - increased clarity and understanding of the reaction mechanism, confidence that the process can be safely scaled up, increases in the selectivity and yield of the process, and confidence that the process may be efficiently transferred to a vendor. Mid-infrared (Mid-IR) is an especially important tool for scale-up - spanning small volume laboratory investigations (ReactIR™, MultiMax) to pilot-scale studies (MonARC™). |  Click to see a preview |
Presenter
Your online presenter, Dr. Wes Walker, has 10 years of experience in the application of mid-IR spectroscopy to monitor and understand chemical processes. Dr. Walker is a Technology and Applications Consultant for our Reaction Analysis team.
Innovative solutions and technology
METTLER TOLEDO is the world leader for in situ reaction monitoring. Our ReactIR™ product line has been extensively used in the pharmaceutical and chemical industries for over 15 years. With over 1,000 systems installed worldwide we have developed the experience and global support network to assist you in the understanding and optimization of your processes.
