Highly reactive chemistries involve compounds or operating conditions that pose significant hazards in research and manufacturing due to high risks of explosion, unwanted human exposure, and poor product quality caused by reaction excursion. Such risks are typically originated from the following characteristics of highly reactive chemistry:
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Due to their effectiveness in enabling a broad range of chemical transformations, many types of highly reactive chemistries offer the preferred synthetic options. As a result, highly reactive chemistry is periodically used by virtually every chemist involved in process research and development for the synthesis of organic compounds such as:
- Active Pharmaceutical Ingredients (API's)
- Specialty polymers
- Agricultural chemicals (e.g., herbicides, pesticides, etc.)
- High energy materials
- Special materials (e.g., nano-particles, chemo-sensors, etc.)
- Organo-catalysts, ligands
To minimize the hazardous risk in process research and development, many highly reactive chemistries have been monitored and controlled effectively using in situ real time analytics to provide a deeper understanding and better control of the reactions without the need for offline sampling and analysis. Efficient optimization of robust and safe processes have been enabled using highly precise and data-rich experimental tools, such as METTLER TOLEDO Automated Lab Reactors with calorimetry and ReactIR™.
Highly Reactive Chemistry Webinar Details
In this Highly Reactive Chemistry webinar, a number of case studies will be presented illustrating how in situ real time analytics have been used in industry to aid in the safe development, scale-up and operation of highly reactive chemistry.