Crystallization processes designed at small scale regularly behave completely differently when scaled initially to pilot plant, and finally to full scale commercial production. This scale up can create significant changes in critical particle properties such as the crystal size, shape, purity and polymorphic form, subsequently impacting the downstream operations. Lasentec® technology has established itself as a fundamental requirement for the optimization of such large scale crystallization processes. The pilot plant is vital in achieving key objectives such as process development, clinical supply manufacture, scale up and transfer. Information on the crystallization step at this stage can decrease the development time required in the pilot plant while subsequently gaining a valuable insight into the impact of scale up on the process. |  Click to preview this Crystallization webinar |
In this on-demand webinar, we introduce and discuss best practice when intstalling a Lasentec® probes in the plant. Topics include:
- Choosing the most suitable instrument model
- Installation options in reactors and pipes
- The importance of probe positioning
- Communication with a DCS
- Real examples from production crystallizations
- Crystallization in the Chemical Industry
- Rapid Crystallization Development and Scale-up using Lasentec® Tools
- Maximizing the Value of Crystallization Experiments with Lasentec®
- Tools for Crystallization Scale-up
- Crystallization: from Screening to Optimization Using Smart Lab Reactors
- Maximizing the Value of Crystallization through Supersaturation Measurement Using ReactIR™