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Understand and Control Process Chemistry

Het overzetten van een chemisch proces van laboratorium naar fabriek is vaak moeilijk vanwege de transfer van de kalibratiegegevens tussen de analyzers. Bij in situ monitoring is offline bemonstering niet meer nodig. ReactIR™ 45P maakt het u mogelijk een proces in het lab te begrijpen en dit proces over te zetten naar de fabriek.
Moeiteloze flow chemistry

Continuous flow chemistry wordt meer wijdverbreid gebruikt in de high value chemicals markt. Het nieuwe FlowIR™ systeem is specifiek ontworpen als een klein, ergonomisch in situ analyse-instrument voor chemici die op dit gebied werkzaam zijn. Het is gebruiksvriendelijk, bespaart reagentia en levert essentiële informatie die nodig is om snel flowreacties te optimaliseren.
De makkelijke manier van organische chemie

Het OptiMax™synthese werkstation herdefinieert de manier waarop organische chemie wordt uitgevoerd, met eenvoudige, nauwkeurige en reproduceerbare werking. Het elimineert het gebruik van rondbodemkolven, olie- en ijsbaden, verwarmingsmantels en zwaarlijvige cryostaten. Intuïtieve handelingen vereenvoudigen de besturing van de experimenten, welke zonder toezicht kunnen lopen.
Best Practices for Crystallization Development White Paper

The latest whitepaper – Best Practices for Crystallization Development: A Review of Modern Techniques – demonstrates the methodology used to quickly understand crystal growth, nucleation, size, and shape from within the crystallizer and optimize critical parameters such as the temperature profile, addition rates, and seeding to improve purity, filtration rates, and batch repeatability.
Onderzoek CH functionalisering met In Situ FTIR

CH functionalisering is een snel groeiend gebied van onderzoek in de afgelopen 20 jaar. In deze context is het belangrijk om het effect van de katalysator, substraat en carbenoid precursors te begrijpen op de snelheid en efficiëntie van rhodium gekatalyseerde reacties. Een van de technieken beschikbaar om hun invloed te bestuderen is ReactIR ™ in situ spectroscopie.

Recent Advances in Organic Chemistry - Metal Catalysed Transformations

Chemical transformations, catalyzed by transition metals, play an important role in the field of catalysis. This white paper, ‘Recent Advances in Organic Chemistry – Metal Catalyzed Transformations’, looks at some of the latest research published in this area.
Best Practices for QbD Experiments

Quality by Design (QbD) consists of rapidly changing process and product development methods used throughout the pharmaceutical industry. QbD studies require the highest quality of experimental equipment and Process Analytical Technology (PAT) to ensure an accurate determination of process variability and maximum confidence in the proposed design space.
Incredible ReactIR 4000 Trade-In Promotion

Do you have a ReactIR™ 4000 that needs upgrading?
METTLER TOLEDO has an offer for you. As a discontinued product, the ReactIR™ 4000 system is no longer available and the support period for your instrument will soon end. Trade-in your ReactIR™ 4000 today and save 15% on a replacement ReactIR™ 45m or ReactIR™ 15 unit.
Verminder de risico's van het opschalen van explosieve compounds

Challenges exist during the development and scale-up of highly energetic materials. In addition to achieving the desired yield, purity, and particle size distribution, process safety issues associated with explosive compounds must also be addressed. Risks can be reduced or eliminated by using reaction calorimetry and in situ FTIR reaction monitoring.
Simple and Cost Effective Reaction Process Monitoring

Whether challenged by space constraints and/or complex installation requirements, ReactIR™ 247 is a unique process-hardened FTIR spectrometer designed to fit into nearly any space without sacrificing the proven performance of ReactIR™ technology.

Designed for classified environments, it is engineered to be simple to use, highly compact, cost effective and have the overall performance required for reaction and process monitoring in kilo labs, pilot plants, hydrogenation labs and production facilities.
White Paper: Process Analytical Technology (PAT) for Biotech

Combine The Benefits of Flow Chemistry and Online Analysis

Take advantage of the combination of flow hydrogenation reactions and real time reaction analysis to deliver a faster way to perform and optimize hydrogenation reactions and receive a 20% discount on one or both of these technologies – available for a limited time only.*
Improve Continuous Process Production With Real-Time Reaction Monitoring and Flow Synthesis

ThalesNano and METTLER TOLEDO announced a collaboration to combine their existing technologies to offer flow reactor technology with real time reaction monitoring for faster reaction optimization and improved continuous process production. The customer-driven collaboration will result in the integration of ThalesNano’s entire flow reactor line with the METTLER TOLEDO ReactIR DS Micro Flow Cell system to take flow chemistry beyond where it is today.
Improve Chemistry Understanding with Reaction Analysis

METTLER TOLEDO announced the release of the ReactIR™ 15 reaction analysis and reaction monitoring system. ReactIR™ 15 is a Fourier Transform Infrared Monitoring (FTIR) instrument that is ideally suited for general, in situ reaction analysis understanding. Progressive technology and software allow this ReactIR™ to be used effortlessly by any chemist, whether skilled in spectroscopy or not.
Advancements in Optimization of Flow Reaction Systems

At the 2010 Fall American Chemical Society (ACS) meeting in Boston, Professor Steven V. Ley, BP (1702) Professor of Organic Chemistry at the University of Cambridge presented a novel approach to the use of flow chemistry as a synthetic technique.
Applications of the RC1e Calorimeter for Process Safety and Scale-Up

Allen M. Beard (Albemarle, USA) reported on the reaction modeling and process development of a fine chemical compound (4-Fluorobenzaldehyde). Kinetic data (ReactIR) and heat of reaction data (RC1e calorimetry) are key components of a safe and efficient scale-up to production.
Process Analytical Technology (PAT) Tools for Pre-Clinical Pharmaceutical R&D

Ben Littler (Vertex Pharmaceuticals, Inc., USA) reported on the use of Process Analytical Technology (PAT) in Pre-Clinical R&D to speed development and reduce time to market. The presented case studies illustrated the use of in situ FTIR reaction monitoring (ReactIR) and heat flow (MultiMax) to meet these objectivies.
New Reaction Analysis Data Sheets

AutoChem Customer Community Site Version 2 Launched

Reduce the risks of highly reactive chemistry

Chemists design synthesis steps involving highly reactive, unstable and toxic reagents or intermediates day by day. Optimization of highly reactive chemistry requires creativity to maximize yield. The process has to be safe and scalable. AutoChem reactors and process analytical technology help researchers quickly characterize and optimize their most difficult chemistry.
New in situ FTIR Reaction Monitoring System

New lab reactor software provides efficient control and data evaluation

MonArc Equipment Qualification Package Now Available

Continuous flow chemistry – verbeterd productkwaliteit en opbrengst

Continuous flow chemistry is waardevol voor de real time verbetering van productkwaliteit en opbrengst. In situ en in real time reactiemonitoring levert met gebruik van ReactIR™ betrouwbare informatie over de reactievoortgang met specifieke informatie over de reactiestart, de omzetting, het tussenstadium en het eindpunt. ReactIR™ blijkt zeer waardevol, zeker bij het volgen van reacties die lastig te bemonsteren zijn.