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Best Practices for Crystallization Development White Paper

The latest whitepaper – Best Practices for Crystallization Development: A Review of Modern Techniques – demonstrates the methodology used to quickly understand crystal growth, nucleation, size, and shape from within the crystallizer and optimize critical parameters such as the temperature profile, addition rates, and seeding to improve purity, filtration rates, and batch repeatability.
Snel, makkelijk en real-time deeltjesanalyse

Focused Beam Reflectance Measurement (FBRM®) verstrekt unieke meting van deeltjes en druppeltjes in geconcentreerde suspensies en emulsies. De nieuwste generatie FBRM-technologie is robuust, veelzijdig en ideaal voor de procesomgeving. Een nieuw ontwerp maakt het zelfs makkelijker om deeltjes te karakteriseren en vlokvorming te analyseren.
Best Practices for QbD Experiments

Quality by Design (QbD) consists of rapidly changing process and product development methods used throughout the pharmaceutical industry. QbD studies require the highest quality of experimental equipment and Process Analytical Technology (PAT) to ensure an accurate determination of process variability and maximum confidence in the proposed design space.
Improve Flocculation Product Quality

When separating solids from a liquid, flocculation is used to maximize the rate and degree of separation. In the paper industry, flocculation is used to maximize production throughput and product quality. Regardless of the process, these goals need to be met by using the least amount of chemicals possible as well as meeting quality assurance requirements. By maximizing throughput, the scale of equipment needed can be reduced, which is especially important with gravity thickeners when conducting flocculation for mining or wastewater.
Faster Crystallization Optimization and Troubleshooting with Process Analytical Technology (PAT)

The latest whitepaper - A Guide to Scale-up of Batch Crystallization from Lab to Plantfeatures case studies examining the use of Process Analytical Technology (PAT) for real-time monitoring of crystallization. The paper focuses on the optimization of crystallization performance, tracking critical process parameters and designing robust, scalable processes.
Powtech/TechnoPharm Innovation Award for FBRM C35 In-Process Particle Characterization Tool

METTLER TOLEDO will be participating at Partec/Powtech/WCPT6 on April 26-29 in Nuremberg, Germany.  METTLER TOLEDO will present three posters and one paper.  Additionally, FBRM® and PVM® particle size distribution technologies will be presented by GlaxoSmithKline, Novartis Pharmaceuticals and GEA Pharma Systems. You can also visit Hall 9/9-620 to see the METTLER TOLEDO particle size distribution product range including FBRM® C35, PVM® V819, and S400 laboratory probes.
Real-time Monitoring of Polymer Particle Growth Kinetics Using FBRM® and PVM®

AutoChem Customer Community Site Version 2 Launched

Research in Flow Assurance

Flow assurance is a serious issue in oil recovery and transport. METTLER TOLEDO Lasentec® technology measures particles and droplets directly in oil under typical conditions. It helps diagnosing the events leading to flow restriction, and supporting the testing of proposed solutions. Avoid extremely costly problems caused by gas hydrates, wax crystallization, asphaltenes or water-oil emulsions.
Evaluate FBRM® data with new powerful data acquisition and interpretation software

First in Situ Probe-Based Technology to Capture Microscope Quality Images

Process Analytical Technology (PAT) for Dissolution Testing and Root Cause Analysis

Asphaltenes, Waxes, Emulsions, and Oil Suspensions: Inline Particle and Droplet Measurements in Dark Crude Oil or Drilling Fluids

Druppelanalyse optimaliseert productiesnelheid van olie

Deeltjeskarakterisering verzekert consistente walspers processen

Bij het walspersen wordt de verdeling van deeltjes beschouwd als een van de meest kritieke parameters die van invloed is op de downstream procesprestatie en productkwaliteit van de uiteindelijke tablet. Het toepassen van deeltjeskarakterisering tijdens het walspersen verbind direct de procescontrole parameters aan de productkwaliteit.